Items where Author is " Kowol Christian R."

Federa Anja and Pitek Rastislav and Dömötör Orsolya and Enyedy Éva Anna and Terenzi Alessio and Caban Monika and Stefanelli Alessia and D’Anna Luisa and White Faye and Heffeter Petra and Kowol Christian R.: Tumor-Targeted Delivery of an EGFR Inhibitor Prodrug via Site-Specific Albumin Conjugation.
JOURNAL OF MEDICINAL CHEMISTRY, 69 (3). pp. 2554-2574. ISSN 0022-2623 (2026)

Pósa Vivien and Federa Anja and Cseh Klaudia and Wenisch Dominik and Spengler Gabriella and May Nóra Veronika and Lihi Norbert and Samu Gergely Ferenc and Jakupec Michael A. and Keppler Bernhard K. and Kowol Christian R. and Enyedy Éva Anna: A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions.
INORGANIC CHEMISTRY, 63 (5). pp. 2401-2417. ISSN 0020-1669 (2024)

Dömötör Orsolya and Mathuber Marlene and Kowol Christian R.: In vitro biodistribution studies on clinically approved FGFR inhibitors ponatinib, nintedanib, erlotinib and the investigational inhibitor KP2692.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 192. ISSN 0928-0987 (2024)

Mosca Elena and Federa Anja and Pirker Christine and Schosserer Markus and Liendl Lisa and Eckhard Margret and Sombke Andy and Dömötör Orsolya and Kirchhofer Dominik and Timelthaler Gerald and Baier Dina and Gurschka Patrizia and Gabler Lisa and Reithofer Michael and Chin Jia Min and Elsayad Kareem and Englinger Bernhard and Tahir Ammar and Kowol Christian R. and Berger Walter: The tyrosine kinase inhibitor Nintedanib induces lysosomal dysfunctionality: Role of protonation-dependent crystallization processes.
CHEMICO-BIOLOGICAL INTERACTIONS, 403. ISSN 0009-2797 (2024)

Pósa Vivien and Stefanelli Alessia and Nunes Julia H. Bormio and Hager Sonja and Mathuber Marlene and May Nóra Veronika and Berger Walter and Keppler Bernhard K. and Kowol Christian R. and Enyedy Éva Anna and Heffeter Petra: Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance.
CANCERS, 14 (18). Terjedelem: 27 p.-Azonosító: 4455. ISSN 2072-6694 (2022)

Pósa Vivien and Hajdu Bálint and Tóth Gábor and Dömötör Orsolya and Kowol Christian R. and Keppler Bernhard K. and Spengler Gabriella and Gyurcsik Béla and Enyedy Éva Anna: The coordination modes of (thio)semicarbazone copper(II) complexes strongly modulate the solution chemical properties and mechanism of anticancer activity.
JOURNAL OF INORGANIC BIOCHEMISTRY, 231. Terjedelem: 13 p-Azonosító: 111786. ISSN 0162-0134 (2022)

Bormio Nunes Julia H. and Hager Sonja and Mathuber Marlene and Pósa Vivien and Roller Alexander and Enyedy Éva Anna and Stefanelli Alessia and Berger Walter and Keppler Bernhard K. and Heffeter Petra and Kowol Christian R.: Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux.
JOURNAL OF MEDICINAL CHEMISTRY, 63. pp. 13719-13732. ISSN 0022-2623 (2020)

Enyedy Éva Anna and May Nóra Veronika and Pape Veronika and Heffeter Petra and Szakács Gergely and Keppler Bernhard K. and Kowol Christian R.: Complex formation and cytotoxicity of Triapine derivatives: a comparative solution study on the effect of the chalcogen atom and NH-methylation.
DALTON TRANSACTIONS, 49. pp. 16887-16902. ISSN 1477-9226 (2020)

Hager Sonja and Pape Veronika and Pósa Vivien and Montsch Bianca and Uhlik Lukas and Szakács Gergely and Tóth Szilárd and Jabronka Nikolett and Keppler Bernhard K. and Kowol Christian R. and Enyedy Éva Anna and Heffeter Petra: High copper complex stability and slow reduction kinetics as key parameters for improved activity, paraptosis induction and impact on drug-resistant cells of anticancer thiosemicarbazones.
ANTIOXIDANTS & REDOX SIGNALING, 33 (6). pp. 395-414. ISSN 1523-0864 (2020)

Mathuber Marlene and Schueffl Hemma and Dömötör Orsolya and Karnthaler Claudia and Enyedy Éva Anna and Heffeter Petra and Kowol Christian R.: Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs.
INORGANIC CHEMISTRY, 59 (23). pp. 17794-17810. ISSN 0020-1669 (2020)

Heffeter Petra and Pape Veronika and Enyedy Éva Anna and Keppler Bernhard K. and Szakács Gergely and Kowol Christian R.: Anticancer thiosemicarbazones: chemical properties, interaction with iron metabolism, and resistance development.
ANTIOXIDANTS & REDOX SIGNALING, 30 (8). pp. 1062-1082. ISSN 1523-0864 (2019)

Kallus Sebastian and Uhlik Lukas and van Schoonhoven Sushilla and Pelivan Karla and Berger Walter and Enyedy Éva Anna and Hofmann Thilo and Heffeter Petra and Kowol Christian R. and Keppler Bernhard K.: Synthesis and biological evaluation of biotin-conjugated anticancer thiosemicarbazones and their iron(III) and copper(II) complexes.
JOURNAL OF INORGANIC BIOCHEMISTRY, 190. pp. 85-97. ISSN 0162-0134 (2019)

Dömötör Orsolya and Pelivan Karla and Borics Attila and Keppler Bernhard K. and Kowol Christian R. and Enyedy Éva Anna: Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational inhibitor KP2187.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 154. pp. 321-331. ISSN 0731-7085 (2018)

Jakusch Tamás and Kozma Károly and Enyedy Éva Anna and Nagy Nóra Veronika and Roller Alexander and Kowol Christian R. and Keppler Bernhard K. and Kiss Tamás: Complexes of pyridoxal thiosemicarbazones formed with vanadium(IV/V) and copper(II): solution equilibrium and structure.
NEW JOURNAL OF CHEMISTRY, 472. pp. 243-253. ISSN 1144-0546 (2018)

Dömötör Orsolya and May Nóra Veronika and Pelivan Karla and Kiss Tamás and Keppler Bernhard K. and Kowol Christian R. and Enyedy Éva Anna: A comparative study of α-N-pyridyl thiosemicarbazones: spectroscopic properties, solution stability and copper(II) complexation.
INORGANICA CHIMICA ACTA, 472 (SI). pp. 264-275. ISSN 0020-1693 (2018)

Kowol Christian R. and Walter Miklós and Pfaff Sarah and Hager Sonja and Kallus Sebastian and Pelivan Karla and Kubanik Mario and Enyedy Éva Anna and Berger Walter and Heffeter Petra and Keppler Bernhard K.: Impact of stepwise NH2-methylation of Triapine on the physico-chemical properties, anticancer activity and resistance circumvention.
JOURNAL OF MEDICINAL CHEMISTRY, 59 (14). pp. 6739-6752. ISSN 0022-2623 (2016)

Kowol Christian R. and Nagy Nóra Veronika and Jakusch Tamás and Roller Alexander and Heffeter Petra and Keppler Bernhard K. and Enyedy Éva Anna: Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones: synthesis, solution equilibrium and bioactivity.
JOURNAL OF INORGANIC BIOCHEMISTRY, 152 (SI). pp. 62-73. ISSN 0162-0134 (2015)

Trondl Robert and Flocke Lea S. and Kowol Christian R. and Heffeter Petra and Jungwirth Ute and Mair Georg E. and Steinborn Ralf and Enyedy Éva Anna and Jakupec Michael A. and Berger Walter and Keppler Bernhard K.: Triapine and a more potent dimethyl derivative induce ER stress in cancer cells.
MOLECULAR PHARMACOLOGY, 85 (3). pp. 451-459. ISSN 0026-895X (2014)

Pichler Verena and Mayr Josef and Heffeter Petra and Dömötör Orsolya and Enyedy Éva Anna and Hermann Gerrit and Groza Diana and Köllensperger Gunda and Galanksi Markus and Berger Walter and Keppler Bernhard K. and Kowol Christian R.: Maleimide-functionalised platinum(IV) complexes as synthetic platform for targeted drug delivery.
CHEMICAL COMMUNICATIONS, 49 (22). pp. 2249-2251. ISSN 1359-7345 (2013)

Enyedy Éva Anna and Zsigó Éva and May Nóra Veronika and Kowol Christian R. and Roller Alexander and Keppler Bernhard K. and Kiss Tamás: Complex-formation ability of salicylaldehyde thiosemicarbazone towards ZnII, CuII, FeII, FeIII and GaIII Ions.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2012 (25). pp. 4036-4047. ISSN 1434-1948 (2012)

Enyedy Éva Anna and Primik Michael F. and Kowol Christian R. and Arion Vladimir B. and Kiss Tamás and Keppler Bernhard K.: Interaction of Triapine and related thiosemicarbazones with iron(III)/(II) and gallium(III): a comparative solution equilibrium study.
DALTON TRANSACTIONS, 40 (22). pp. 5895-5905. ISSN 1477-9226 (2011)

Popović-Bijelić Ana and Kowol Christian R. and Lind Maria E.S. and Luo Jinghui and Himo Fahmi and Enyedy Éva Anna and Arion Vladimir B. and Gräslund Astrid: Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): A combined experimental and theoretical study.
JOURNAL OF INORGANIC BIOCHEMISTRY, 105 (11). pp. 1422-1431. ISSN 0162-0134 (2011)

Enyedy Éva Anna and May Nóra Veronika and Zsigó Éva and Kowol Christian R. and Arion Vladimir B and Keppler Bernhard K. and Kiss Tamás: Comparative Solution Equilibrium Study of the Interactions of Copper(II), Iron(II) and Zinc(II) with Triapine (3-Aminopyridine-2-carbaldehyde Thiosemicarbazone) and Related Ligands.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2010 (11). pp. 1717-1728. ISSN 1434-1948 (2010)