Pósa Vivien; Stefanelli Alessia; Nunes Julia H. Bormio; Hager Sonja; Mathuber Marlene; May Nóra Veronika; Berger Walter; Keppler Bernhard K.; Kowol Christian R.; Enyedy Éva Anna; Heffeter Petra:
Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance.
CANCERS, 14 (18).
Terjedelem: 27 p.-Azonosító: 4455.
ISSN 2072-6694
(2022)
Bormio Nunes Julia H.; Hager Sonja; Mathuber Marlene; Pósa Vivien; Roller Alexander; Enyedy Éva Anna; Stefanelli Alessia; Berger Walter; Keppler Bernhard K.; Heffeter Petra; Kowol Christian R.:
Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux.
JOURNAL OF MEDICINAL CHEMISTRY, 63.
pp. 13719-13732.
ISSN 0022-2623
(2020)
Enyedy Éva Anna; May Nóra Veronika; Pape Veronika; Heffeter Petra; Szakács Gergely; Keppler Bernhard K.; Kowol Christian R.:
Complex formation and cytotoxicity of Triapine derivatives: a comparative solution study on the effect of the chalcogen atom and NH-methylation.
DALTON TRANSACTIONS, 49.
pp. 16887-16902.
ISSN 1477-9226
(2020)
Hager Sonja; Pape Veronika; Pósa Vivien; Montsch Bianca; Uhlik Lukas; Szakács Gergely; Tóth Szilárd; Jabronka Nikolett; Keppler Bernhard K.; Kowol Christian R.; Enyedy Éva Anna; Heffeter Petra:
High copper complex stability and slow reduction kinetics as key parameters for improved activity, paraptosis induction and impact on drug-resistant cells of anticancer thiosemicarbazones.
ANTIOXIDANTS & REDOX SIGNALING, 33 (6).
pp. 395-414.
ISSN 1523-0864
(2020)
Mathuber Marlene; Schueffl Hemma; Dömötör Orsolya; Karnthaler Claudia; Enyedy Éva Anna; Heffeter Petra; Kowol Christian R.:
Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs.
INORGANIC CHEMISTRY, 59 (23).
pp. 17794-17810.
ISSN 0020-1669
(2020)
Heffeter Petra; Pape Veronika; Enyedy Éva Anna; Keppler Bernhard K.; Szakács Gergely; Kowol Christian R.:
Anticancer thiosemicarbazones: chemical properties, interaction with iron metabolism, and resistance development.
ANTIOXIDANTS & REDOX SIGNALING, 30 (8).
pp. 1062-1082.
ISSN 1523-0864
(2019)
Kallus Sebastian; Uhlik Lukas; van Schoonhoven Sushilla; Pelivan Karla; Berger Walter; Enyedy Éva Anna; Hofmann Thilo; Heffeter Petra; Kowol Christian R.; Keppler Bernhard K.:
Synthesis and biological evaluation of biotin-conjugated anticancer thiosemicarbazones and their iron(III) and copper(II) complexes.
JOURNAL OF INORGANIC BIOCHEMISTRY, 190.
pp. 85-97.
ISSN 0162-0134
(2019)
Kowol Christian R.; Walter Miklós; Pfaff Sarah; Hager Sonja; Kallus Sebastian; Pelivan Karla; Kubanik Mario; Enyedy Éva Anna; Berger Walter; Heffeter Petra; Keppler Bernhard K.:
Impact of stepwise NH2-methylation of Triapine on the physico-chemical properties, anticancer activity and resistance circumvention.
JOURNAL OF MEDICINAL CHEMISTRY, 59 (14).
pp. 6739-6752.
ISSN 0022-2623
(2016)
Kowol Christian R.; Nagy Nóra Veronika; Jakusch Tamás; Roller Alexander; Heffeter Petra; Keppler Bernhard K.; Enyedy Éva Anna:
Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones: synthesis, solution equilibrium and bioactivity.
JOURNAL OF INORGANIC BIOCHEMISTRY, 152 (SI).
pp. 62-73.
ISSN 0162-0134
(2015)
Trondl Robert; Flocke Lea S.; Kowol Christian R.; Heffeter Petra; Jungwirth Ute; Mair Georg E.; Steinborn Ralf; Enyedy Éva Anna; Jakupec Michael A.; Berger Walter; Keppler Bernhard K.:
Triapine and a more potent dimethyl derivative induce ER stress in cancer cells.
MOLECULAR PHARMACOLOGY, 85 (3).
pp. 451-459.
ISSN 0026-895X
(2014)
Pichler Verena; Mayr Josef; Heffeter Petra; Dömötör Orsolya; Enyedy Éva Anna; Hermann Gerrit; Groza Diana; Köllensperger Gunda; Galanksi Markus; Berger Walter; Keppler Bernhard K.; Kowol Christian R.:
Maleimide-functionalised platinum(IV) complexes as synthetic platform for targeted drug delivery.
CHEMICAL COMMUNICATIONS, 49 (22).
pp. 2249-2251.
ISSN 1359-7345
(2013)