Marć Małgorzata Anna; Domínguez-Álvarez Enrique; Latacz Gniewomir; Doroz-Płonka Agata; Sanmartín Carmen; Spengler Gabriella; Handzlik Jadwiga:
Pharmaceutical and Safety Profile Evaluation of Novel Selenocompounds with Noteworthy Anticancer Activity.
PHARMACEUTICS, 14 (2).
Terjedelem: 25 p.-Azonosító: 367.
ISSN 1999-4923
(2022)
Ali Wesam; Garbo Sabrina; Kincses Annamária; Nové Márta; Spengler Gabriella; Di Bello Elisabetta; Honkisz-Orzechowska Ewelina; Karcz Tadeusz; Szymanska Ewa; Zesławska Ewa; Starek Małgorzata; Dąbrowska Monika; Nitek Wojciech; Kucwaj-Brysz Katarzyna; Pyka Patryk; Fioravanti Rossella; Jacob Claus; Battistelli Cecilia; Zwergel Clemens; Handzlik Jadwiga:
Seleno-vs. thioether triazine derivatives in search for new anticancer agents overcoming multidrug resistance in lymphoma.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 243.
ISSN 0223-5234
(2022)
Kaczor Aneta; Szemerédi Nikoletta; Kucwaj-Brysz Katarzyna; Dąbrowska Monika; Starek Małgorzata; Latacz Gniewomir; Spengler Gabriella; Handzlik Jadwiga:
Computer‐aided search for 5‐arylideneimidazolone anticancer agents able to overcome ABCB1‐based multidrug resistance.
CHEMMEDCHEM, 16 (15).
pp. 2386-2401.
ISSN 1860-7179
(2021)
Żesławska Ewa; Kucwaj-Brysz Katarzyna; Kincses Annamária; Spengler Gabriella; Szymańska Ewa; Czopek Anna; Marć Małgorzata Anna; Kaczor Aneta; Nitek Wojciech; Domínguez-Álvarez Enrique; Latacz Gniewomir; Kieć-Kononowicz Katarzyna; Handzlik Jadwiga:
An insight into the structure of 5-spiro aromatic derivatives of imidazolidine-2,4-dione, a new group of very potent inhibitors of tumor multidrug resistance in T-lymphoma cells.
BIOORGANIC CHEMISTRY, 109.
Terjedelem: 18 p-Azonosító: 104735.
ISSN 0045-2068
(2021)
Ali Wesam; Spengler Gabriella; Kincses Annamária; Nové Márta; Battistelli Cecilia; Latacz Gniewomir; Starek Małgorzata; Dabrowska Monika; Honkisz-Orzechowska Ewelina; Romanelli Annalisa; Rasile Manuela Monica; Szymanska Ewa; Jacob Claus; Zwergel Clemens; Handzlik Jadwiga:
Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 200.
Terjedelem: 17-Azonosító: 112435.
ISSN 0223-5234
(2020)
Szczepańska Katarzyna; Kincses Annamária; Vincze Klaudia; Szymańska Ewa; Latacz Gniewomir; Kuder Kamil J.; Stark Holger; Spengler Gabriella; Handzlik Jadwiga; Kieć-Kononowicz Katarzyna:
N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H3 receptor and cancer resistance proteins.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 30 (22).
ISSN 0960-894X
(2020)
Kaczor Aneta; Nové Márta; Kincses Annamária; Spengler Gabriella; Szymańska Ewa; Latacz Gniewomir; Handzlik Jadwiga:
Search for ABCB1 Modulators Among 2-Amine-5-Arylideneimidazolones as a New Perspective to Overcome Cancer Multidrug Resistance.
MOLECULES, 25 (9).
Terjedelem: 24-Azonosító: 2258.
ISSN 1420-3049
(2020)
Żesławska Ewa; Kincses Annamária; Spengler Gabriella; Nitek Wojciech; Tejchman Waldemar; Handzlik Jadwiga:
Pharmacophoric features for a very potent 5-spirofluorenehydantoin inhibitor of cancer efflux pump ABCB1, based on X-ray analysis.
CHEMICAL BIOLOGY & DRUG DESIGN, 93 (5).
pp. 844-853.
ISSN 1747-0277
(2019)
Nasim Muhammad Jawad; Witek Karolina; Kincses Annamária; Abdin Ahmad Yaman; Żesławska Ewa; Gajdács Márió; Spengler Gabriella; Małgorzata Anna Marć; Wojciech Nitek F; Gniewomir Latacz; Karczewska Elżbieta; Kieć -Kononowicz Katarzyna; Handzlik Jadwiga; Jacob Claus:
Pronounced activity of aromatic selenocyanates against multidrug resistant ESKAPE bacteria.
NEW JOURNAL OF CHEMISTRY, 43 (15).
pp. 6021-6031.
ISSN 1144-0546
(2019)
Domínguez‐Álvarez Enrique; Łażewska Dorota; Szabó Zsanett; Hagenow Stefanie; Reiner David; Gajdács Márió; Spengler Gabriella; Stark Holger; Handzlik Jadwiga; Kieć-Kononowicz Katarzyna:
The Search for Histamine H 4 Receptor Ligands with Anticancer Activity among Novel (Thio)urea Derivatives.
CHEMISTRYSELECT, 4 (36).
pp. 10943-10952.
ISSN 2365-6549
(2019)
Gajdács Márió; Handzlik Jadwiga; Sanmartín Carmen; Domínguez-Álvarez Enrique; Spengler Gabriella:
Rákellenes és efflux pumpa gátló hatású szelénvegyületek ADME tulajdonságainak becslése számítógépes módszerrel [Prediction of ADME properties for selenocompounds with anticancer and efflux pump inhibitory activity using preliminary computational methods].
ACTA PHARMACEUTICA HUNGARICA, 88 (2).
pp. 67-73.
ISSN 0001-6659
(2018)
Gajdács Márió; Handzlik Jadwiga; Sanmartín Carmen; Domínguez-Álvarez Enrique; Spengler Gabriella:
Szerves szelénvegyületek mint daganatellenes szerek: kísérleti eredmények in vitro vastagbél adenokarcinóma modellen [Organoselenium compounds as antitumor agents: In vitro evaluation on a colon cancer model system].
ACTA PHARMACEUTICA HUNGARICA, 88 (2).
pp. 59-65.
ISSN 0001-6659
(2018)
Gajdács Márió; Spengler Gabriella; Sanmartín Carmen; Marć Małgorzata Anna; Handzlik Jadwiga; Domínguez-Álvarez Enrique:
Selenoesters and selenoanhydrides as novel multidrug resistance reversing agents: A confirmation study in a colon cancer MDR cell line.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 27 (4).
pp. 797-802.
ISSN 0960-894X
(2017)
Zeslawska Ewa; Kincses Annamária; Spengler Gabriella; Nitek Wojciech; Wyrzuc Karolina; Kieć-Kononowicz Katarzyna; Handzlik Jadwiga:
The 5-aromatic hydantoin-3-acetate derivatives as inhibitors of the tumour multidrug resistance efflux pump P-glycoprotein (ABCB1): Synthesis, crystallographic and biological studies.
Bioorganic & Medicinal Chemistry, 24 (12).
pp. 2815-2822.
ISSN 0968-0896
(2016)
Domínguez-Álvarez Enrique; Gajdács Márió; Spengler Gabriella; Palop Juan Antonio; Marć Małgorzata Anna; Kieć-Kononowicz Katarzyna; Amaral Leonard; Molnár József; Jacob Claus; Handzlik Jadwiga; Sanmartín Carmen:
Identification of selenocompounds with promising properties to reverse cancer multidrug resistance.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 26 (12).
pp. 2821-2824.
ISSN 0960-894X
(2016)
Handzlik Jadwiga; Spengler Gabriella; Mastek Beata; Dela Anna; Molnár József; Amaral Leonard; Kieć-Kononowicz Katarzyna:
5-Arylidene(thio)hydantoin derivatives as modulators of cancer efflux pump.
ACTA POLONIAE PHARMACEUTICA, 69 (1).
pp. 149-156.
ISSN 0001-6837
(2012)