Szerző: " Mernyák Erzsébet"

Bózsity-Faragó Noémi; Nagy Viktória; Szabó Johanna; Pálházi Balázs; Kele Zoltán; Resch Vivien; Paragi Gábor; Zupkó István; Minorics Renáta; Mernyák Erzsébet: Synthesis of Estrone Heterodimers and Evaluation of Their In Vitro Antiproliferative Activity.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 25 (8). ISSN 1661-6596 (2024)

Senobar Tahaei Seyyed Ashkan; Kulmány Ágnes; Minorics Renáta; Kiss Anita; Szabó Zoltán; Germán Péter; Szebeni Gábor; Gémes Nikolett; Mernyák Erzsébet; Zupkó István: Antiproliferative and Antimetastatic Properties of 16-Azidomethyl Substituted 3-O-Benzyl Estrone Analogs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24 (18). ISSN 1661-6596 (2023)

Zottel A.; Jójárt Rebeka; Ágoston H.; Hafner E.; Lipušček N.; Mernyák Erzsébet; Lanišnik Rižner T.: Cytotoxic effect of 13α-estrane derivatives on breast, endometrial and ovarian cancer cell lines.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 232. ISSN 0960-0760 (2023)

Kovács Édua; Ali Hazhmat; Minorics Renáta; Traj Péter; Resch Vivien Erzsébet; Paragi Gábor; Bruszel Bella; Zupkó István; Mernyák Erzsébet: Synthesis and Antiproliferative Activity of Steroidal Diaryl Ethers.
MOLECULES, 28 (3). ISSN 1420-3049 (2023)

Hlogyik Tamás; Laczkó-Rigó Réka; Bakos Éva; Poór Miklós; Kele Zoltán; Laczka Csilla; Mernyák Erzsébet: Synthesis and in vitro photodynamic activity of aza-BODIPY-based photosensitizers.
ORGANIC & BIOMOLECULAR CHEMISTRY, 21 (29). pp. 6018-6027. ISSN 1477-0520 (2023)

Peřina Miroslav; Kiss Anita; Mernyák Erzsébet; Mada Lukáš; Schneider Gyula; Jorda Radek: Synthesis of hydrocortisone esters targeting androgen and glucocorticoid receptors in prostate cancer in vitro.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 229. ISSN 0960-0760 (2023)

Tuerkova Alzbeta; Ungvári Orsolya; Laczkó-Rigó Réka; Mernyák Erzsébet; Szakács Gergely; Laczka Csilla; Zdrazil Barbara: Data-Driven Ensemble Docking to Map Molecular Interactions of Steroid Analogs with Hepatic Organic Anion Transporting Polypeptides.
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 61 (6). pp. 3109-3127. ISSN 1549-9596 (2021)

Jójárt Rebeka; Laczkó-Rigó Réka; Klement Máté; Kőhl Gabriella; Kecskeméti Gábor; Laczka Csilla; Mernyák Erzsébet: Design, synthesis and biological evaluation of novel estrone phosphonates as high affinity organic anion-transporting polypeptide 2B1 (OATP2B1) inhibitors.
BIOORGANIC CHEMISTRY, 112. Terjedelem: 12 p-Azonosító: 104914. ISSN 0045-2068 (2021)

Mernyák Erzsébet; Bartha Sándor; Kóczán Lili; Jójárt Rebeka; Resch Vivien; Paragi Gábor; Vágvölgyi Máté; Hunyadi Attila; Bruszel Bella; Zupkó István; Minorics Renáta: Microwave-assisted Phospha-Michael addition reactions in the 13 alpha-oestrone series and in vitro antiproliferative properties.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 1931-1937. ISSN 1475-6366 (2021)

Kiss Anita; Jójárt Rebeka; Mernyák Erzsébet; Bartha Sándor; Minorics Renáta; Zupkó István; Schneider Gyula: Novel preparation of substituted oxazolines condensed to d-ring of estrane skeleton and characterization of their antiproliferative properties.
STEROIDS, 176. Terjedelem: 6 p-Azonosító: 108911. ISSN 0039-128X (2021)

Laczkó-Rigó Réka; Bakos Éva; Jójárt Rebeka; Tömböly Csaba; Mernyák Erzsébet; Laczka Csilla: Selective antiproliferative effect of C-2 halogenated 13α-estrones on cells expressing Organic anion-transporting polypeptide 2B1 (OATP2B1).
TOXICOLOGY AND APPLIED PHARMACOLOGY, 429. ISSN 0041-008X (2021)

Sinreih Maša; Jójárt Rebeka; Kele Zoltán; Büdefeld Tomaž; Paragi Gábor; Mernyák Erzsébet; Rižner Tea Lanišnik: Synthesis and evaluation of AKR1C inhibitory properties of A-ring halogenated oestrone derivatives.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 1500-1508. ISSN 1475-6366 (2021)

Jójárt Rebeka; Senobar Tahaei Seyyed Ashkan; Trungel-Nagy Péter; Kele Zoltán; Minorics Renáta; Paragi Gábor; Zupkó István; Mernyák Erzsébet: Synthesis and evaluation of anticancer activities of 2- or 4-substituted 3-(N-benzyltriazolylmethyl)-13α-oestrone derivatives.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 58-67. ISSN 1475-6366 (2021)

Traj Péter; Ali Hazhmat; Németh Anett; Dajcs Sámuel Trisztán; Tömösi Ferenc; Lanisnik-Rizner Tea; Zupkó István; Mernyák Erzsébet: Transition metal-catalyzed A-ring C–H activations and C(sp2)–C(sp2) couplings in the 13α-estrone series and in vitro evaluation of antiproliferative properties.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 36 (1). pp. 895-902. ISSN 1475-6366 (2021)

Jójárt Rebeka; Ali Hazhmat; Horváth Gergely; Kele Zoltán; Zupkó István; Mernyák Erzsébet: Pd-Catalyzed Suzuki–Miyaura couplings and evaluation of 13α-estrone derivatives as potential anticancer agents.
STEROIDS, 164. Terjedelem: 10 p.-Azonosító: 108731. ISSN 0039-128X (2020)

Laczkó-Rigó Réka; Jójárt Rebeka; Mernyák Erzsébet; Bakos Éva; Tuerkova Alzbeta; Zdrazil Barbara; Laczka Csilla: Structural dissection of 13-epiestrones based on the interaction with human Organic anion-transporting polypeptide, OATP2B1.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 200. Terjdelem: 10 p.-Azonosító: 105652. ISSN 0960-0760 (2020)

Stefan Jopp; Peter Ehlers; Nagyné Frank Éva; Mernyák Erzsébet; Schneider Gyula; Wölfling János; Villinger Alexander; Langer Peter: Site-Selective Synthesis of 3,17-Diaryl-1,3,5,16-estratetraenes.
SYNLETT, 30. A-E. ISSN 0936-5214 (2019)

Kiss Anita; Wölfling János; Mernyák Erzsébet; Nagyné Frank Éva; Benke Zsanett Amália; Zupkó István; Schneider Gyula: Stereocontrolled synthesis of the four possible 3-methoxy and 3-benzyloxy-16-triazolyl-methyl-estra-17-ol hybrids and their antiproliferative activities.
STEROIDS, 152. Azonosító: 108500-Terjedelem: 14 p. ISSN 0039-128X (2019)

Kiss Anita; Wölfling János; Mernyák Erzsébet; Nagyné Frank Éva; Gyovai András; Kulmány Ágnes Erika; Zupkó István; Schneider Gyula: Stereoselective Synthesis of New Type of Estradiol Hybrid Molecules and their Antiproliferative Activities.
STEROIDS, 148. pp. 63-72. ISSN 0039-128X (2019)

Keglevich András Imre; Zsíros Vivian; Keglevich Péter; Szigetvári Áron; Dékány Miklós; Szántay Csaba, ifj; Mernyák Erzsébet; Wölfling János; Hazai László: Synthesis and in vitro antitumor effect of new vindoline-steroid hybrids.
CURRENT ORGANIC CHEMISTRY, 23 (8). pp. 959-967. ISSN 1385-2728 (2019)

Herman Bianka Edina; Kiss Anita; Wölfling János; Mernyák Erzsébet; Szécsi Mihály; Schneider Gyula: Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 34 (1). pp. 1271-1286. ISSN 1475-6366 (2019)

Jójárt Rebeka; Traj Péter; Kovács Édua; Horváth Ágnes; Schneider Gyula; Szécsi Mihály; Pál Attila; Paragi Gábor; Mernyák Erzsébet: Synthesis, Biological Evaluation and Docking Studies of 13-Epimeric 10-fluoro- and 10-Chloroestra-1,4-dien-3-ones as Potential Aromatase Inhibitors.
MOLECULES, 24 (9). Paper 1783-18 p. ISSN 1420-3049 (2019)

Sinka Izabella; Kiss Anita; Mernyák Erzsébet; Wölfling János; Schneider Gyula; Ocsovszki Imre; Kuo Ching-Ying; Wang Hui-Chun; Zupkó István: Antiproliferative and antimetastatic properties of 3-benzyloxy-6-hydroxymethylene-estradiol analogs against breast cancer cell lines.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 123. pp. 362-370. ISSN 0928-0987 (2018)

Gyovai András; Minorics Renáta; Kiss Anita; Mernyák Erzsébet; Schneider Gyula; Szekeres András; Kerekes Erika Beáta; Ocsovszki Imre; Zupkó István: Antiproliferative properties of newly synthesized 19-nortestosterone analogs without substantial androgenic activity.
FRONTIERS IN PHARMACOLOGY, 9. Terjedelem: 11 p.-Azonosító: 825. ISSN 1663-9812 (2018)

Jopp Stefan; Wallaschkowski Tina; Ehlers Peter; Nagyné Frank Éva; Schneider Gyula; Wölfling János; Mernyák Erzsébet: Chemoselective Suzuki-Miyaura reactions of 4-bromo-3-O-triflyl-estrone. Synthesis and atropisomerism of arylated estrones.
TETRAHEDRON, 74 (23). pp. 2825-2836. ISSN 0040-4020 (2018)

Kiss Anita; Mernyák Erzsébet; Wölfling János; Szőllősi György; Schneider Gyula: Improved stereoselective synthesis of 3-methoxy- and 3-benzyloxy-16-hydroxymethyl-13α-estra-1,3,5(10)-trien-17-ol isomers by transfer hydrogenation using chiral Ru catalysts.
REACTION KINETICS MECHANISMS AND CATALYSIS, 125 (1). pp. 47-53. ISSN 1878-5190 (2018)

Jójárt Rebeka; Pécsy Balázs; Keglevich György; Szécsi Mihály; Rigó Réka; Laczka Csilla; Kecskeméti Gábor; Mernyák Erzsébet: Pd-Catalyzed microwave-assisted synthesis of phosphonated 13α-estrones as potential OATP2B1, 17β-HSD1 and/or STS inhibitors.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 14. pp. 2838-2845. ISSN 1860-5397 (2018)

Kiss Anita; Mernyák Erzsébet; Wölfling János; Sinka Izabella; Zupkó István; Schneider Gyula: Stereoselective synthesis of the four 16-hydroxymethyl-3-methoxy- and 16- hydroxymethyl-3-benzyloxy-13α-estra-1,3,5(10)-trien-17-ol isomers and their antiproliferative activities.
STEROIDS, 134. pp. 67-77. ISSN 0039-128X (2018)

Bacsa Ildikó; Herman Bianka Edina; Jójárt Rebeka; Herman Kevin Stefán; Wölfling János; Schneider Gyula; Varga Mónika; Tömböly Csaba; Lanisnik Rizner Tea; Szécsi Mihály; Mernyák Erzsébet: Synthesis and structure–activity relationships of 2- and/or 4-halogenated 13β- and 13α-estrone derivatives as enzyme inhibitors of estrogen biosynthesis.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 33 (1). pp. 1271-1282. ISSN 1475-6366 (2018)

Froehlich Tony; Kiss Anita; Wölfling János; Mernyák Erzsébet; Kulmány Ágnes Erika; Minorics Renáta; Zupkó István; Leidenberger Maria; Friedrich Oliver; Kappes Barbara; Hahn Friedrich; Marschall Manfred; Schneider Gyula; Tsogoeva Svetlana B.: Synthesis of Artemisinin-Estrogen Hybrids Highly Active against HCMV, P-falciparum, and Cervical and Breast Cancer.
ACS MEDICINAL CHEMISTRY LETTERS, 9 (11). pp. 1128-1133. ISSN 1948-5875 (2018)

Kiss Anita; Herman Bianka Edina; Görbe Tamás; Mernyák Erzsébet; Molnár Barnabás; Wölfling János; Szécsi Mihály; Schneider Gyula: Synthesis of novel 17-triazolyl-androst-5-en-3-ol epimers via Cu(I)-catalyzed azide-alkyne cycloaddition and their inhibitory effect on 17α-hydroxylase/C17,20-lyase.
STEROIDS, 135. pp. 79-91. ISSN 0039-128X (2018)

Bacsa Ildikó; Konc Csilla; Orosz Anna Boglárka; Kecskeméti Gábor; Rigó Réka; Laczka Csilla; Mernyák Erzsébet: Synthesis of novel C-2- or C-15-labeled BODIPY—estrone conjugates.
MOLECULES, 23 (4). Terjedelem: 13 p. -Azonosító: 821. ISSN 1420-3049 (2018)

Bacsa Ildikó; Szemerédi Dávid; Wölfling János; Schneider Gyula; Fekete Lilla; Mernyák Erzsébet: The first Pd-catalyzed Buchwald–Hartwig aminations at C-2 or C-4 in the estrone series.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 14. pp. 998-1003. ISSN 1860-5397 (2018)

Bózsity Noémi; Minorics Renáta; Szabó Johanna; Mernyák Erzsébet; Schneider Gyula; Wölfling János; Wang Hui-Chun; Wu Chin-Chung; Ocsovszki Imre; Zupkó István: Mechanism of antiproliferative action of a new D-secoestrone-triazole derivative in cervical cancer cells and its effect on cancer cell motility.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 165. pp. 247-257. ISSN 0960-0760 (2017)

Bodnár Brigitta; Mernyák Erzsébet; Szabó Johanna; Wölfling János; Schneider Gyula; Zupkó István; Kupihár Zoltán; Kovács Lajos: Synthesis and in vitro investigation of potential antiproliferative monosaccharide-D-secoestrone bioconjugates.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 27 (9). pp. 1938-1942. ISSN 0960-894X (2017)

Bacsa Ildikó; Jójárt Rebeka; Wölfling János; Schneider Gyula; Herman Bianka Edina; Szécsi Mihály; Mernyák Erzsébet: Synthesis of novel 13α-estrone derivatives by Sonogashira coupling as potential 17β-HSD1 inhibitors.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 13. pp. 1303-1309. ISSN 1860-5397 (2017)

Herman Bianka Edina; Szabó Johanna; Bacsa Ildikó; Wölfling János; Schneider Gyula; Bálint Mónika Enikő; Hetényi Csaba; Mernyák Erzsébet; Szécsi Mihály: Comparative investigation of the in vitro inhibitory potencies of 13-epimeric estrones and D-secoestrones towards 17β-hydroxysteroid dehydrogenase type 1.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 31 (Suppl. 3). pp. 61-69. ISSN 1475-6366 (2016)

Schneider Gyula; Kiss Anita; Mernyák Erzsébet; Benke Zsanett Amália; Wölfling János; Nagyné Frank Éva; Bózsity Noémi; Gyovai András; Minorics Renáta; Zupkó István: Stereocontrolled synthesis of the four 16-hydroxymethyl-19-nortestosterone isomers and their antiproliferative activities.
STEROIDS, 105. pp. 113-120. ISSN 0039-128X (2016)

Szabó Johanna; Pataki Zoltán; Wölfling János; Schneider Gyula; Bózsity Noémi; Minorics Renáta; Zupkó István; Mernyák Erzsébet: Synthesis and biological evaluation of 13α-estrone derivatives as potential antiproliferative agents.
STEROIDS, 113. pp. 14-21. ISSN 0039-128X (2016)

Bodnár Brigitta; Mernyák Erzsébet; Wölfling János; Schneider Gyula; Herman Bianka Edina; Szécsi Mihály; Sinka Izabella; Zupkó István; Kupihár Zoltán; Kovács Lajos: Synthesis and biological evaluation of triazolyl 13α-estrone–nucleoside bioconjugates.
MOLECULES, 21 (9). Paper 1212-16 p. ISSN 1420-3049 (2016)

Szabó Johanna; Jerkovics Nóra; Schneider Gyula; Wölfling János; Bózsity Noémi; Minorics Renáta; Zupkó István; Mernyák Erzsébet: Synthesis and in Vitro Antiproliferative Evaluation of C-13 Epimers of Triazolyl-d-Secoestrone Alcohols: The First Potent 13alpha-d-Secoestrone Derivative.
MOLECULES, 21 (5). Terjedelem: 13 p.-Azonosító: 611. ISSN 1420-3049 (2016)

Szabó Johanna; Bacsa Ildikó; Wölfling János; Schneider Gyula; Zupkó István; Varga Mónika; Herman Bianka Edina; Kalmár László; Szécsi Mihály; Mernyák Erzsébet: Synthesis and in vitro pharmacological evaluation of N-[(1-benzyl-1,2,3-triazol-4-yl)methyl]-carboxamides on d-secoestrone scaffolds.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 31 (4). pp. 574-579. ISSN 1475-6366 (2016)

Mernyák Erzsébet: Szelektív antitumor hatású ösztronszármazékok szintézise.
MAGYAR KÉMIKUSOK LAPJA, 71 (5). pp. 145-146. ISSN 0025-0163 (2016)

Bacsa Ildikó; Jójárt Rebeka; Schneider Gyula; Wölfling János; Maróti Péter; Herman Bianka Edina; Szécsi Mihály; Mernyák Erzsébet: Synthesis of A-ring halogenated 13alpha-estrone derivatives as potential 17beta-HSD1 inhibitors.
Steroids, 104. pp. 230-236. ISSN 0039-128X (2015)

Huber Judit; Wölfling János; Schneider Gyula; Ocsovszki Imre; Varga Mónika; Zupkó István; Mernyák Erzsébet: Synthesis of antiproliferative 13α-d-homoestrones via Lewis acid-promoted one-pot Prins–Ritter reactions of d-secosteroidal δ-alkenyl-aldehydes.
STEROIDS, 102. pp. 76-84. ISSN 0039-128X (2015)

Szabó Nikoletta; Iványi Zoltán; Szécsi Mihály; Julesz János; Mernyák Erzsébet; Huber Judit; Wölfling János; Minorics Renáta; Zupkó István; Schneider Gyula: Synthesis of methoxycarbonylpyrazolylandrostene derivatives, and their potential inhibitory effect on androgen biosynthesis and cell proliferation.
Steroids, 98. pp. 143-152. ISSN 0039-128X (2015)

Schneider Gyula; Görbe Tamás Ferenc; Mernyák Erzsébet; Wölfling János; Holczbauer Tamás; Czugler Mátyás; Sohár Pál; Minorics Renáta; Zupkó István: Synthesis of novel 17-(5’-iodo)triazolyl-3-methoxyestrane epimers via Cu(I)-catalyzed azide-alkyne cycloadditon, and an evaluation of their cytotoxic activity in vitro.
STEROIDS, 98. pp. 153-165. ISSN 0039-128X (2015)

Mernyák Erzsébet; Kovács Ida; Minorics Renáta; Sere Péter; Czégány Dóra; Sinka Izabella; Wölfling János; Schneider Gyula; Újfaludi Zsuzsanna; Boros Imre Miklós; Ocsovszki Imre; Varga Mónika; Zupkó István: Synthesis of trans-16-triazolyl-13α-methyl-17-estradiol diastereomers and the effects of structural modifications on their in vitro antiproliferative activities.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 150. pp. 123-134. ISSN 0960-0760 (2015)

Minorics Renáta; Bózsity Noémi; Molnár Judit; Wölfling János; Mernyák Erzsébet; Schneider Gyula; Ocsovszki Imre; Zupkó István: A molecular understanding of d-homoestrone-induced G2/M cell cycle arrest in HeLa human cervical carcinoma cells.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 19 (10). pp. 2365-2374. ISSN 1582-1838 (2015)

Mernyák Erzsébet; Szabó Johanna; Bacsa Ildikó; Huber Judit; Schneider Gyula; Minorics Renáta; Bózsity Noémi; Zupkó István; Varga Mónika; Bikádi Zsolt; Hazai Eszter; Wölfling János: Syntheses and Antiproliferative Effects of D-homo- and D-secoestrones.
STEROIDS, 87. pp. 128-136. ISSN 0039-128X (2014)

Mernyák Erzsébet; Fiser Gabriella; Szabó Johanna; Bodnár Brigitta; Schneider Gyula; Kovács Ida Jusztina; Ocsovszki Imre; Zupkó István; Wölfling János: Synthesis and in vitro antiproliferative evaluation of D-secooxime derivatives of 13β- and 13α-estrone.
STEROIDS, 89. pp. 47-55. ISSN 0039-128X (2014)

Mernyák Erzsébet; Huber Judit; Szabó Johanna; Schneider Gyula; Hetényi Anasztázia; Márk László; Maász Gábor; Berényi Ágnes; Kovács Ida Jusztina; Minorics Renáta; Zupkó István; Wölfling János: Cycloaddition of Steroidal Cyclic Nitrones to C=N Dipolarophiles: Stereoselective Synthesis and Antiproliferative Effects of Oxadiazolidinones in the Estrone Series.
STEROIDS, 78 (10). pp. 1021-1028. ISSN 0039-128X (2013)

Minorics Renáta; Bózsity Noémi; Wölfling János; Mernyák Erzsébet; Schneider Gyula; Márki Árpád; Falkay György; Ocsovszki Imre; Zupkó István: Antiproliferative effect of normal and 13-epi-d-homoestrone and their 3-methyl ethers on human reproductive cancer cell lines.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 132. pp. 168-175. ISSN 0960-0760 (2012)

Mernyák Erzsébet; Benedek Gabriella; Schneider Gyula; Wölfling János: Stereoselective synthesis of condensed aza-D-homoestrone derivatives by 1,3-dipolar cycloaddition.
SYNLETT, 2005 (4). pp. 637-639. ISSN 0936-5214 (2005)

Mernyák Erzsébet; Schonecker Bruno; Lange Corinna; Kotteritzsch Manuela; Gorls Helmar; Wölfling János; Schneider Gyula: Addition reactions at the 16(17) double bond of 3-methoxy-13 alpha-estra-1,3,5(10),16-tetraene.
STEROIDS, 68 (3). pp. 289-295. ISSN 0039-128X (2003)