Szerző: " Kowol Christian R."

Pósa Vivien; Federa Anja; Cseh Klaudia; Wenisch Dominik; Spengler Gabriella; May Nóra Veronika; Lihi Norbert; Samu Gergely Ferenc; Jakupec Michael A.; Keppler Bernhard K.; Kowol Christian R.; Enyedy Éva Anna: A Comparative Study on the Complexation of the Anticancer Iron Chelator VLX600 with Essential Metal Ions.
INORGANIC CHEMISTRY, 63 (5). pp. 2401-2417. ISSN 0020-1669 (2024)

Dömötör Orsolya; Mathuber Marlene; Kowol Christian R.: In vitro biodistribution studies on clinically approved FGFR inhibitors ponatinib, nintedanib, erlotinib and the investigational inhibitor KP2692.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 192. ISSN 0928-0987 (2024)

Pósa Vivien; Stefanelli Alessia; Nunes Julia H. Bormio; Hager Sonja; Mathuber Marlene; May Nóra Veronika; Berger Walter; Keppler Bernhard K.; Kowol Christian R.; Enyedy Éva Anna; Heffeter Petra: Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance.
CANCERS, 14 (18). Terjedelem: 27 p.-Azonosító: 4455. ISSN 2072-6694 (2022)

Pósa Vivien; Hajdu Bálint; Tóth Gábor; Dömötör Orsolya; Kowol Christian R.; Keppler Bernhard K.; Spengler Gabriella; Gyurcsik Béla; Enyedy Éva Anna: The coordination modes of (thio)semicarbazone copper(II) complexes strongly modulate the solution chemical properties and mechanism of anticancer activity.
JOURNAL OF INORGANIC BIOCHEMISTRY, 231. Terjedelem: 13 p-Azonosító: 111786. ISSN 0162-0134 (2022)

Bormio Nunes Julia H.; Hager Sonja; Mathuber Marlene; Pósa Vivien; Roller Alexander; Enyedy Éva Anna; Stefanelli Alessia; Berger Walter; Keppler Bernhard K.; Heffeter Petra; Kowol Christian R.: Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux.
JOURNAL OF MEDICINAL CHEMISTRY, 63. pp. 13719-13732. ISSN 0022-2623 (2020)

Enyedy Éva Anna; May Nóra Veronika; Pape Veronika; Heffeter Petra; Szakács Gergely; Keppler Bernhard K.; Kowol Christian R.: Complex formation and cytotoxicity of Triapine derivatives: a comparative solution study on the effect of the chalcogen atom and NH-methylation.
DALTON TRANSACTIONS, 49. pp. 16887-16902. ISSN 1477-9226 (2020)

Hager Sonja; Pape Veronika; Pósa Vivien; Montsch Bianca; Uhlik Lukas; Szakács Gergely; Tóth Szilárd; Jabronka Nikolett; Keppler Bernhard K.; Kowol Christian R.; Enyedy Éva Anna; Heffeter Petra: High copper complex stability and slow reduction kinetics as key parameters for improved activity, paraptosis induction and impact on drug-resistant cells of anticancer thiosemicarbazones.
ANTIOXIDANTS & REDOX SIGNALING, 33 (6). pp. 395-414. ISSN 1523-0864 (2020)

Mathuber Marlene; Schueffl Hemma; Dömötör Orsolya; Karnthaler Claudia; Enyedy Éva Anna; Heffeter Petra; Kowol Christian R.: Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs.
INORGANIC CHEMISTRY, 59 (23). pp. 17794-17810. ISSN 0020-1669 (2020)

Heffeter Petra; Pape Veronika; Enyedy Éva Anna; Keppler Bernhard K.; Szakács Gergely; Kowol Christian R.: Anticancer thiosemicarbazones: chemical properties, interaction with iron metabolism, and resistance development.
ANTIOXIDANTS & REDOX SIGNALING, 30 (8). pp. 1062-1082. ISSN 1523-0864 (2019)

Kallus Sebastian; Uhlik Lukas; van Schoonhoven Sushilla; Pelivan Karla; Berger Walter; Enyedy Éva Anna; Hofmann Thilo; Heffeter Petra; Kowol Christian R.; Keppler Bernhard K.: Synthesis and biological evaluation of biotin-conjugated anticancer thiosemicarbazones and their iron(III) and copper(II) complexes.
JOURNAL OF INORGANIC BIOCHEMISTRY, 190. pp. 85-97. ISSN 0162-0134 (2019)

Dömötör Orsolya; Pelivan Karla; Borics Attila; Keppler Bernhard K.; Kowol Christian R.; Enyedy Éva Anna: Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational inhibitor KP2187.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 154. pp. 321-331. ISSN 0731-7085 (2018)

Jakusch Tamás; Kozma Károly; Enyedy Éva Anna; Nagy Nóra Veronika; Roller Alexander; Kowol Christian R.; Keppler Bernhard K.; Kiss Tamás: Complexes of pyridoxal thiosemicarbazones formed with vanadium(IV/V) and copper(II): solution equilibrium and structure.
NEW JOURNAL OF CHEMISTRY, 472. pp. 243-253. ISSN 1144-0546 (2018)

Dömötör Orsolya; May Nóra Veronika; Pelivan Karla; Kiss Tamás; Keppler Bernhard K.; Kowol Christian R.; Enyedy Éva Anna: A comparative study of α-N-pyridyl thiosemicarbazones: spectroscopic properties, solution stability and copper(II) complexation.
INORGANICA CHIMICA ACTA, 472 (SI). pp. 264-275. ISSN 0020-1693 (2018)

Kowol Christian R.; Walter Miklós; Pfaff Sarah; Hager Sonja; Kallus Sebastian; Pelivan Karla; Kubanik Mario; Enyedy Éva Anna; Berger Walter; Heffeter Petra; Keppler Bernhard K.: Impact of stepwise NH2-methylation of Triapine on the physico-chemical properties, anticancer activity and resistance circumvention.
JOURNAL OF MEDICINAL CHEMISTRY, 59 (14). pp. 6739-6752. ISSN 0022-2623 (2016)

Kowol Christian R.; Nagy Nóra Veronika; Jakusch Tamás; Roller Alexander; Heffeter Petra; Keppler Bernhard K.; Enyedy Éva Anna: Vanadium(IV/V) complexes of Triapine and related thiosemicarbazones: synthesis, solution equilibrium and bioactivity.
JOURNAL OF INORGANIC BIOCHEMISTRY, 152 (SI). pp. 62-73. ISSN 0162-0134 (2015)

Trondl Robert; Flocke Lea S.; Kowol Christian R.; Heffeter Petra; Jungwirth Ute; Mair Georg E.; Steinborn Ralf; Enyedy Éva Anna; Jakupec Michael A.; Berger Walter; Keppler Bernhard K.: Triapine and a more potent dimethyl derivative induce ER stress in cancer cells.
MOLECULAR PHARMACOLOGY, 85 (3). pp. 451-459. ISSN 0026-895X (2014)

Pichler Verena; Mayr Josef; Heffeter Petra; Dömötör Orsolya; Enyedy Éva Anna; Hermann Gerrit; Groza Diana; Köllensperger Gunda; Galanksi Markus; Berger Walter; Keppler Bernhard K.; Kowol Christian R.: Maleimide-functionalised platinum(IV) complexes as synthetic platform for targeted drug delivery.
CHEMICAL COMMUNICATIONS, 49 (22). pp. 2249-2251. ISSN 1359-7345 (2013)

Enyedy Éva Anna; Zsigó Éva; May Nóra Veronika; Kowol Christian R.; Roller Alexander; Keppler Bernhard K.; Kiss Tamás: Complex-formation ability of salicylaldehyde thiosemicarbazone towards ZnII, CuII, FeII, FeIII and GaIII Ions.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2012 (25). pp. 4036-4047. ISSN 1434-1948 (2012)

Enyedy Éva Anna; Primik Michael F.; Kowol Christian R.; Arion Vladimir B.; Kiss Tamás; Keppler Bernhard K.: Interaction of Triapine and related thiosemicarbazones with iron(III)/(II) and gallium(III): a comparative solution equilibrium study.
DALTON TRANSACTIONS, 40 (22). pp. 5895-5905. ISSN 1477-9226 (2011)

Popović-Bijelić Ana; Kowol Christian R.; Lind Maria E.S.; Luo Jinghui; Himo Fahmi; Enyedy Éva Anna; Arion Vladimir B.; Gräslund Astrid: Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): A combined experimental and theoretical study.
JOURNAL OF INORGANIC BIOCHEMISTRY, 105 (11). pp. 1422-1431. ISSN 0162-0134 (2011)

Enyedy Éva Anna; May Nóra Veronika; Zsigó Éva; Kowol Christian R.; Arion Vladimir B; Keppler Bernhard K.; Kiss Tamás: Comparative Solution Equilibrium Study of the Interactions of Copper(II), Iron(II) and Zinc(II) with Triapine (3-Aminopyridine-2-carbaldehyde Thiosemicarbazone) and Related Ligands.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2010 (11). pp. 1717-1728. ISSN 1434-1948 (2010)