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Bormio Nunes, Julia H., Hager, Sonja, Mathuber, Marlene, Pósa, Vivien, Roller, Alexander, Enyedy, Éva Anna, Stefanelli, Alessia, Berger, Walter, Keppler, Bernhard K., Heffeter, Petra, Kowol, Christian R.:
Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux.
JOURNAL OF MEDICINAL CHEMISTRY, 63.
pp. 13719-13732.
ISSN 0022-2623
(2020)
Hager, Sonja, Pape, Veronika, Pósa, Vivien, Montsch, Bianca, Uhlik, Lukas, Szakács, Gergely, Tóth, Szilárd, Jabronka, Nikolett, Keppler, Bernhard K., Kowol, Christian R., Enyedy, Éva Anna, Heffeter, Petra:
High copper complex stability and slow reduction kinetics as key parameters for improved activity, paraptosis induction and impact on drug-resistant cells of anticancer thiosemicarbazones.
ANTIOXIDANTS & REDOX SIGNALING, 33 (6).
pp. 395-414.
ISSN 1523-0864
(2020)
Kowol, Christian R., Walter, Miklós, Pfaff, Sarah, Hager, Sonja, Kallus, Sebastian, Pelivan, Karla, Kubanik, Mario, Enyedy, Éva Anna, Berger, Walter, Heffeter, Petra, Keppler, Bernhard K.:
Impact of stepwise NH2-methylation of Triapine on the physico-chemical properties, anticancer activity and resistance circumvention.
JOURNAL OF MEDICINAL CHEMISTRY, 59 (14).
pp. 6739-6752.
ISSN 0022-2623
(2016)