%X The present study examines an alternative and innovative mechanical ventilation modality in improving oxygen delivery, CO 2 clearance, and respiratory mechanical abnormalities in a clinically relevant experimental model of capnoperitoneum. Our data reveal that high-frequency oscillations combined with conventional ventilation improve gas exchange, with intratracheal oscillations being more effective than extrathoracic oscillations in this clinically relevant translational model. %A PetĂĄk Ferenc %A SĂźdy Roberta %A Diaper John %A Fontao Fabienne %A Bizzotto Davide %A DellacĂ Raffaele L. %A Habre Walid %A Schranc Ălmos %J JOURNAL OF APPLIED PHYSIOLOGY %L publicatio36160 %R MTMT:34798171 10.1152/japplphysiol.00881.2023 %N 4 %T Benefits of intratracheal and extrathoracic high-frequency percussive ventilation in a model of capnoperitoneum %P 928-937 %V 136 %D 2024 %O Department of Medical Physics and Informatics, University of Szeged, Szeged, Hungary Unit for Anesthesiological Investigations, Department of Acute Medicine, University of Geneva, Geneva, Switzerland Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy Export Date: 15 May 2024 CODEN: JAPHE Correspondence Address: PetĂĄk, F.; Department of Medical Physics and Informatics, Hungary; email: petak.ferenc@med.u-szeged.hu Chemicals/CAS: carbon dioxide, 124-38-9, 58561-67-4; Carbon Dioxide Funding details: OTKA-NKFIH K138032 Funding text 1: This work was supported by a Hungarian Basic Research Council Grant OTKA-NKFIH K138032. %I szte