TY  - JOUR
ID  - publicatio35820
EP  - 16
SN  - 1471-2377
Y1  - 2025///
VL  - 25
UR  - https://doi.org/10.1186/s12883-025-04042-6
AV  - public
TI  - The effect of transcranial direct current stimulation and inhibitory control training on depression and anxiety among post-stroke individuals
IS  - 1
N1  - Journal Article; Randomized Controlled Trial
JF  - BMC NEUROLOGY
A1  -  Kazinczi Csaba
A1  -  Szépfalusi Noémi
A1  -  Németh Viola Luca
A1  -  Holczer Adrienn
A1  -  Jakab Katalin
A1  -  Vécsei László
A1  -  Klivényi Péter
A1  -  Must Anita
A1  -  Racsmány Mihály
N2  - Recent research has highlighted the role of fronto-parietal brain networks and cognitive control in mood disorders. Transcranial direct current stimulation (tDCS) and computer-based cognitive training are used in post-stroke rehabilitation. This study examined the combined effects ofof computer-based inhibitory control training (ICCT) and anodal tDCS on post-stroke depression and anxiety.Thirty-five participants were randomly assigned to one of three groups: active tDCS treatment (A), sham tDCS treatment with ICCT (T), or active tDCS with ICCT (AT), for a duration of ten days. Primary outcome measures included the Beck Depression Inventory (BDI), Hamilton Depression Rating Scale (HAM-D), and Spielberger's State-Trait Anxiety Inventory (STAI-S/T). Statistical analysis was performed using a Mixed-model Analysis of Variance, with supplementary Bayesian analysis.The AT group showed a significant improvement in BDI scores (p < .001), whereas no significant effects were observed on the HAM-D, STAI-T, or STAI-S scales.The combination of tDCS and ICCT reduced depressive symptoms as measured by the BDI; while no significant effects were found with either treatment alone. Further research is needed to explore the mechanisms behind the synergistic effects in the treatment of post-stroke mood disorders.
ER  -