%R MTMT:1880328 10.1002/prac.19943360609
%O Z9: 1
WC: Chemistry, Applied; Chemistry, Multidisciplinary
%I szgyaoe
%N 6
%P 525-529
%X The synthesis of ten new thyrotropin-releasing hormone analogues (15-24) which contain uncoded amino acids (L- and D-homoleucine, L- and D-homophenylalanine, L-homoproline and 6-ketopipecolic acid) is described here. The peptide bond formation was achieved in solution phase using pentafluorophenyl ester activation of the N-protected amino acids. The analogues were tested for their ability to release thyrotropin and for CNS activities and proved to be fully inactive.
%J JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG
%D 1994
%A  Somlai Csaba
%A  BalĂĄspiri L
%T Synthesis of Analogues of Thyrotropin-Releasing Hormone
%L publicatio31990
%V 336