%0 Journal Article
%@ 0941-1216
%A  Somlai Csaba
%A  Baláspiri L
%A Orvosi Vegytani Intézet SZTE / SZAOK OVI [2000-],
%D 1994
%F publicatio:31990
%J JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG
%N 6
%P 525-529
%T Synthesis of Analogues of Thyrotropin-Releasing Hormone
%U http://publicatio.bibl.u-szeged.hu/31990/
%V 336
%X The synthesis of ten new thyrotropin-releasing hormone analogues (15-24) which contain uncoded amino acids (L- and D-homoleucine, L- and D-homophenylalanine, L-homoproline and 6-ketopipecolic acid) is described here. The peptide bond formation was achieved in solution phase using pentafluorophenyl ester activation of the N-protected amino acids. The analogues were tested for their ability to release thyrotropin and for CNS activities and proved to be fully inactive.
%Z Z9: 1 WC: Chemistry, Applied; Chemistry, Multidisciplinary