%V 31
%A  Kóbor Jenő
%A  LĂĄzĂĄr JĂĄnos
%A  FĂźlĂśp Ferenc
%A  BernĂĄth GĂĄbor
%D 1994
%X In contrast with earlier literature data [7], both acrylic esters and acrylonitrile underwent Michael addition to 1-methyl-3,4-dihydroisoquinolines 14 to yield the diesters 5-9 or the dinitrile 10, respectively. Compounds S-10 were converted by Claisen condensation to 1-[(3'-methoxycarbonyl- or 1-[(3'-ethoxycarbonyl-4'-oxo)-1-cyclohexyl]-3,4-dihydroisoquinoline derivatives 11-16. Several derivatives of 12 were prepared. The new compounds possess various pharmacological actions.
%P 825-828
%I szgyaoe
%R MTMT:28001 10.1002/jhet.5570310423
%J JOURNAL OF HETEROCYCLIC CHEMISTRY
%L publicatio31967
%N 4
%T Saturated heterocycles. Part 209. Synthesis of 1‐cyclohexyl‐substituted isoquinoline derivatives