relation: http://publicatio.bibl.u-szeged.hu/31967/
title: Saturated heterocycles. Part 209. Synthesis of 1‐cyclohexyl‐substituted isoquinoline derivatives
creator:  Kóbor Jenő
creator:  Lázár János
creator:  Fülöp Ferenc
creator:  Bernáth Gábor
subject: 01.04. Kémiai tudományok
subject: 03.01. Általános orvostudomány
description: In contrast with earlier literature data [7], both acrylic esters and acrylonitrile underwent Michael addition to 1-methyl-3,4-dihydroisoquinolines 14 to yield the diesters 5-9 or the dinitrile 10, respectively. Compounds S-10 were converted by Claisen condensation to 1-[(3'-methoxycarbonyl- or 1-[(3'-ethoxycarbonyl-4'-oxo)-1-cyclohexyl]-3,4-dihydroisoquinoline derivatives 11-16. Several derivatives of 12 were prepared. The new compounds possess various pharmacological actions.
date: 1994
type: Folyóiratcikk
type: PeerReviewed
format: text
identifier: http://publicatio.bibl.u-szeged.hu/31967/1/aok_klny_69_94.pdf
identifier:     Kóbor Jenő;  Lázár János;  Fülöp Ferenc;  Bernáth Gábor: Saturated heterocycles. Part 209. Synthesis of 1‐cyclohexyl‐substituted isoquinoline derivatives.   JOURNAL OF HETEROCYCLIC CHEMISTRY, 31 (4).  pp. 825-828.  ISSN 0022-152X (1994)     
identifier: doi:10.1002/jhet.5570310423
relation: https://doi.org/10.1002/jhet.5570310423
relation: 28001
language: eng