TY  - JOUR
VL  - 19
A1  -  Gyulai Rolland Péter
A1  -  Hunyadi János
A1  -  Kenderessy Szabó Anna
A1  -  Kemény Lajos
A1  -  Dobozy Attila
IS  - 4
ID  - publicatio31958
SN  - 0307-6938
UR  - https://doi.org/10.1111/j.1365-2230.1994.tb01201.x
SP  - 309
EP  - 311
JF  - CLINICAL AND EXPERIMENTAL DERMATOLOGY
N2  - It is generally accepted that keratinocyte migration plays a critical role in the process of wound healing. A study was therefore made of the migratory response of freshly separated and cultured human keratinocytes to factors with chemotactic properties for a variety of cells. Interleukin-1alpha (IL-1alpha), interferon-gamma (IFN-gamma), interleukin-8 (IL-8), and tumour necrosis factor alpha (TNF-alpha) were tested for their chemotactic effectiveness in a modified Boyden chamber assay. IFN-gamma, IL-1alpha and IL-8 were demonstrated to serve as chemoattractants for freshly separated keratinocytes. For cultured cells, however, only IFN-gamma was found to display chemotactic properties. The findings demonstrate that there is significant difference between the chemotactic behaviour of freshly separated and cultured cells.
Y1  - 1994///
AV  - restricted
TI  - Chemotaxis of freshly separated and cultured human keratinocytes
ER  -