relation: http://publicatio.bibl.u-szeged.hu/31958/ title: Chemotaxis of freshly separated and cultured human keratinocytes creator: Gyulai Rolland Péter creator: Hunyadi János creator: Kenderessy Szabó Anna creator: Kemény Lajos creator: Dobozy Attila subject: 03.02. Klinikai orvostan description: It is generally accepted that keratinocyte migration plays a critical role in the process of wound healing. A study was therefore made of the migratory response of freshly separated and cultured human keratinocytes to factors with chemotactic properties for a variety of cells. Interleukin-1alpha (IL-1alpha), interferon-gamma (IFN-gamma), interleukin-8 (IL-8), and tumour necrosis factor alpha (TNF-alpha) were tested for their chemotactic effectiveness in a modified Boyden chamber assay. IFN-gamma, IL-1alpha and IL-8 were demonstrated to serve as chemoattractants for freshly separated keratinocytes. For cultured cells, however, only IFN-gamma was found to display chemotactic properties. The findings demonstrate that there is significant difference between the chemotactic behaviour of freshly separated and cultured cells. date: 1994 type: Folyóiratcikk type: PeerReviewed format: text identifier: http://publicatio.bibl.u-szeged.hu/31958/1/aok_klny_36_94.pdf identifier: Gyulai Rolland Péter; Hunyadi János; Kenderessy Szabó Anna; Kemény Lajos; Dobozy Attila: Chemotaxis of freshly separated and cultured human keratinocytes. CLINICAL AND EXPERIMENTAL DERMATOLOGY, 19 (4). pp. 309-311. ISSN 0307-6938 (1994) identifier: doi:10.1111/j.1365-2230.1994.tb01201.x relation: https://doi.org/10.1111/j.1365-2230.1994.tb01201.x relation: 105842 language: eng relation: info:eu-repo/semantics/altIdentifier/doi/10.1111/j.1365-2230.1994.tb01201.x rights: info:eu-repo/semantics/restrictedAccess