relation: http://publicatio.bibl.u-szeged.hu/31737/
title: Furosemid-tartalmú kúpok előállítása, in vitro vizsgálata és a preklinikai alkalmazás tapasztalatai
creator:  Regdon Géza
creator:  Fazekas Tamás
creator:  Regdon Géza (ifj.)
creator:  Selmeczi Béla
subject: 03.01. Általános orvostudomány
subject: 03.02. Klinikai orvostan
subject: 03.05. Egyéb orvostudományok
description: Rectal suppositories containing Furosemide (4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid) and Furosemide Sodium were formulated with various suppository bases. The in vitro drug release of Massa Estarinum 299 proved to be the best from among the vehicles having various physical-chemical properties. The diuretic effect of the two suppositories was compared in a prospective, cross-over clinical trial including 8 patients. Both preparations have induced and increase of urine flow, which was comparable to the diuretic effect of the tablet. Thus the possibility of rectal use has been added to the modalities of therapeutic Furosemide administration.
date: 1997
type: Folyóiratcikk
type: PeerReviewed
format: text
identifier: http://publicatio.bibl.u-szeged.hu/31737/1/aok_klny_415_97.pdf
identifier:     Regdon Géza;  Fazekas Tamás;  Regdon Géza (ifj.);  Selmeczi Béla: Furosemid-tartalmú kúpok előállítása, in vitro vizsgálata és a preklinikai alkalmazás tapasztalatai.   ACTA PHARMACEUTICA HUNGARICA, 67 (1).  pp. 19-23.  ISSN 0001-6659 (1997)     
relation: 1767249
language: hun
relation: info:eu-repo/semantics/altIdentifier/doi/
rights: info:eu-repo/semantics/restrictedAccess