relation: http://publicatio.bibl.u-szeged.hu/31382/
title: Syntheses and transformations of azeto[2,1-a]- and -[2,1- b]isoquinolines and azeto[1 ',2 ': 1,2]pyrido[3,4-b]indoles
creator:  Fülöp Ferenc
creator:  Bernáth Gábor
subject: 01.04. Kémiai tudományok
subject: 03.01. Általános orvostudomány
description: The syntheses, transformations and some of the biological features of azeto[2,1-a]- and -[2,1-b]isoquinolines and azeto[1',2':1,2]pyrido[3,4-b]indoles are reviewed. Both angularly and linearly fused azetidine derivatives of isoquinolines are known. As concerns the related pyridoindoles, only the angularly fused azeto[1',2':1,2]pyrido[3,4-b]indoles have been prepared and investigated. The most interesting and characteristic transformations of azetoisoquinolines and azeto[1',2':1,2]pyrido[3,4-b]indoles are the ring enlargement reactions; these result, for example, in eight-membered ring derivatives which were difficult to synthesize by earlier methods. Such derivatives are versatile intermediates for the synthesis of biologically important compounds. Some of the azetoisoquinolin-2-ones synthesized and tested to date display weak antibiotic activity. Several other azetoisoquinolines exhibit a wide range of pharmacological activities.
date: 1999
type: Folyóiratcikk
type: PeerReviewed
format: text
identifier: http://publicatio.bibl.u-szeged.hu/31382/1/aok_klny_77_99.pdf
identifier:     Fülöp Ferenc;  Bernáth Gábor: Syntheses and transformations of azeto[2,1-a]- and -[2,1- b]isoquinolines and azeto[1 ',2 ': 1,2]pyrido[3,4-b]indoles.   CURRENT ORGANIC CHEMISTRY, 3.  pp. 1-24.  ISSN 1385-2728 (1999)     
relation: 27968
language: eng
relation: info:eu-repo/semantics/altIdentifier/doi/
rights: info:eu-repo/semantics/restrictedAccess