relation: http://publicatio.bibl.u-szeged.hu/30979/
title: Substituent effects in the ring-chain tautomerism of 1-aryl-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazines
creator:  Szatmári István
creator:  Martinek Tamás
creator:  Lázár László
creator:  Koch Andreas
creator:  Kleinpeter Erich
creator:  Fülöp Ferenc
subject: 03.01.06. Farmakológia és gyógyszerészet
description: The condensation of Betti base analog aminonaphthols with substituted benzaldehydes or aliph. aldehydes led to 1,3-diaryl-2,3-dihydro-1H-naphth[1,2e][1,3]oxazines (16-22) and 3-alkyl-1-aryl-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazines (23-29), which proved to be three-component (r1-o-r2, 16-22) or two-component (r1-r2, 23-29) tautomeric mixts. in CDCl3 at 300 K. The electronic effects of the 3-aryl or 3-alkyl groups on the tautomeric ratios could be described by the equation log KX = ρσ+ + log KX=H (16-22) and log KR = 7.88Va + 0.55 (23-29) resp. Study of the influence of aryl substituents at position 1 indicated that in the trans form a stereoelectronic effect is present; this was supported by dual substituent parameter treatment of the 13C chem. shift changes induced by Ph substituents. [on SciFinder(R)]
date: 2003
type: Folyóiratcikk
type: PeerReviewed
format: text
identifier: http://publicatio.bibl.u-szeged.hu/30979/1/aok_klny_326_03.pdf
identifier:     Szatmári István;  Martinek Tamás;  Lázár László;  Koch Andreas;  Kleinpeter Erich;  Fülöp Ferenc: Substituent effects in the ring-chain tautomerism of 1-aryl-2,3-dihydro-1H-naphth[1,2-e][1,3]oxazines.   ANNALS OF WEST UNIVERSITY OF TIMISOARA-SERIES CHEMISTRY, 12 (3).  pp. 175-182.  ISSN 1224-9513 (2003)     
relation: 3258704
language: eng