TY - CHAP PB - International Society for Optics and Photonics (SPIE) EP - 1-614418-12 T2 - Medical Imaging 2006: Image Processing SN - 0819464236; 9780819464231 M1 - 6144 N2 - Three-dimensional (3D) stress echocardiography is a novel technique for diagnosing cardiac dysfunction, by comparing wall motion of the left ventricle under different stages of stress. For quantitative comparison of this motion, it is essential to register the ultrasound data. We propose an intensity based rigid registration method to retrieve two-dimensional (2D) four-chamber (4C), two-chamber, and short-axis planes from the 3D data set acquired in the stress stage, using manually selected 2D planes in the rest stage as reference. The algorithm uses the Nelder-Mead simplex optimization to find the optimal transformation of one uniform scaling, three rotation, and three translation parameters. We compared registration using the SAD, SSD, and NCC metrics, performed on four resolution levels of a Gaussian pyramid. The registration's effectiveness was assessed by comparing the 3D positions of the registered apex and mitral valve midpoints and 4C direction with the manually selected results. The registration was tested on data from 20 patients. Best results were found using the NCC metric on data downsampled with factor two: mean registration errors were 8.1mm, 5.4mm, and 8.0° in the apex position, mitral valve position, and 4C direction respectively. The errors were close to the interobserver (7.1mm, 3.8mm, 7.4°) and intraobserver variability (5.2mm, 3.3mm, 7.0°), and better than the error before registration (9.4mm, 9.0mm, 9.9°). We demonstrated that the registration algorithm visually and quantitatively improves the alignment of rest and stress data sets, performing similar to manual alignment. This will improve automated analysis in 3D stress echocardiography. A1 - Leung KYE A1 - Van Stralen M A1 - Voormolen MM A1 - Van Burken G A1 - Nemes Attila A1 - Ten Cate FJ A1 - Geleijnse ML A1 - De Jong N A1 - Van Der Steen AFW A1 - Reiber JHC A1 - Bosch JG TI - Registration of 2D cardiac images to real-time 3D ultrasound volumes for 3D stress echocardiography SP - 614418 CY - Bellingham (WA) ID - publicatio30753 Y1 - 2006/// UR - https://doi.org/10.1117/12.652107 T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE AV - restricted ER -