relation: http://publicatio.bibl.u-szeged.hu/25945/ title: Impact of Clinical and Morphological Factors on Long-Term Mortality in Patients with Myocardial Bridge creator: Bárczi György creator: Becker Dávid creator: Sydó Nóra creator: Ruzsa Zoltán creator: Vágó Hajnalka creator: Oláh Attila creator: Merkely Béla Péter subject: 03.02. Klinikai orvostan description: Although myocardial bridging (MB) has been intensively investigated using different methods, the effect of bridge morphology on long-term outcome is still doubtful. We aimed at describing the anatomical differences in coronary angiography between symptomatic and non-symptomatic LAD myocardial bridges and to investigate the influence of clinical and morphological factors on long-term mortality. In our retrospective, long-term, single center study we found relevant MB on the left anterior descendent (LAD) coronary artery in 146 cases during a two-year period, when 11,385 patients underwent coronary angiography due to angina pectoris. Patients were divided into two groups: those with myocardial bridge only (LAD-MBneg, n = 78) and those with associated obstructive coronary artery disease (LAD-MBpos, n = 68). Clinical factors, morphology of bridge by quantitative coronary analysis and ten-year long mortality data were collected. The LAD-MBneg group was associated with younger age and decreased incidence of diabetes mellitus, as well as with increased minimal diameter to reference diameter ratio (LAD-MBneg 54.5 (13.1)% vs. LAD-MBpos 46.5 (16.4)%, p = 0.016), while there was a tendency towards longer lesions and higher vessel diameter values compared to the LAD-MBpos group. The LAD-MBpos group was associated with increased mortality compared to the LAD-MBneg group. The analysis of our data showed that morphological parameters of LAD bridge did not influence long-term mortality, either in the overall population or in the LAD-MBneg patients. Morphological parameters of LAD bridge did not influence long-term mortality outcomes; therefore, it suggests that anatomical differences might not predict long-term outcomes and should not influence therapy. date: 2022 type: Folyóiratcikk type: PeerReviewed format: text identifier: http://publicatio.bibl.u-szeged.hu/25945/1/Barczi.pdf identifier: Bárczi György; Becker Dávid; Sydó Nóra; Ruzsa Zoltán; Vágó Hajnalka; Oláh Attila; Merkely Béla Péter: Impact of Clinical and Morphological Factors on Long-Term Mortality in Patients with Myocardial Bridge. Journal of Cardiovascular Development and Disease, 9 (5). ISSN 2308-3425 (2022) identifier: doi:10.3390/jcdd9050129 relation: https://doi.org/10.3390/jcdd9050129 relation: 32842412 language: eng