%T Outcomes and timing of endoscopic retrograde cholangiopancreatography for acute biliary pancreatitis
%X Background Indication of endoscopic retrograde cholangiopancreatography (ERCP) in acute biliary pancreatitis (ABP) is challenging. Aims In this retrospective study, we analyzed real-world data to understand the ERCP practice in ABP in Hungarian centers. Methods Clinical data on ABP patients (2013â2015) were extracted from our large multicentric database. Outcomes, quality indicators and the role of early timing of ERCP (<24 h from admission) were analyzed. Results There were 356 patients with ABP. ERCP was performed in 267 (75%). Performance indicators of ERCP proved to be suboptimal with a biliary cannulation rate of 84%. Successful vs unsuccessful cannulation of naĂŻve papilla resulted in lower rates of local [22.9% vs 40.9%, (P = 0.012)] and systemic [4.9% vs 13.6%, (P = 0.042)] complications. Successful vs unsuccessful clearance resulted in lower rates of local complications [22.5% vs 40.8%, (P = 0.008)]. Successful cannulation and drainage correlated with less severe course of ABP [3.6% vs 15.9%, (P = 0.001) and 4.1% vs 12.2%, (P = 0.033)] respectively. A tendency of an increased rate of local complications was observed if ERCP was performed later [<24 h: 21.1% (35/166); between 24â48 h: 23.4% (11/47); >48h: 37.2% (16/43) (P = 0.088)]. Conclusion Optimization of ERCP indication in ABP patients is critical as suboptimal ERCP practices in ABP without definitive stone detection are associated with poorer clinical outcomes.
%D 2019
%I szte
%J DIGESTIVE AND LIVER DISEASE
%O CN: Hungarian Pancreatic Study Group
Journal Article; Multicenter Study
Funding Agency and Grant Number: Economic Development and Innovation Operative Programme Grant from the National Research, Development and Innovation Office [GINOP 2.3.2-15-372-2016-00048]; Human Resources Development Operational Programme Grant from the National Research, Development and Innovation Office [EFOP-3.6.2-16-2017-00006]; Momentum Grant from the Hungarian Academy of Sciences [LP2014-10/2014]; Janos Bolyai Research Scholarship of the Hungarian Academy of SciencesHungarian Academy of Sciences; new national excellence program of the Ministry of Human Capacities [UNKP-18-4]; [KH125678]; [K116634]; [K120335]
Funding text: This study was supported by Project Grants (KH125678 and K116634 to PH, K120335 to TT), the Economic Development and Innovation Operative Programme Grant (GINOP 2.3.2-15-372-2016-00048 to PH) and Human Resources Development Operational Programme Grant (EFOP-3.6.2-16-2017-00006 to PH) from the National Research, Development and Innovation Office, by a Momentum Grant from the Hungarian Academy of Sciences (LP2014-10/2014 to PH), by the Janos Bolyai Research Scholarship of the Hungarian Academy of Sciences (to AP) and the UNKP-18-4 new national excellence program of the Ministry of Human Capacities (to AP). Funders had no role in study design, data collection, analysis, interpretation of the findings, and preparation of the manuscript.
Export Date: 19 June 2020
CODEN: DLDIF
Export Date: 22 June 2020
CODEN: DLDIF
Export Date: 23 November 2020
CODEN: DLDIF
Szent GyĂśrgy Teaching Hospital of FejĂŠr County, SzĂŠkesfehĂŠrvĂĄr, Hungary
Institute for Translational Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Institute of Bioanalysis and Institute for Translational Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Bajcsy-Zsilinszky Teaching Hospital of Semmelweis University, Budapest, Hungary
First Department of Medicine, University of Szeged, Szeged, Hungary
First Department of Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Heim PĂĄl National Institute for Pediatrics, Budapest, Hungary
BMKK, Dr. RĂŠthy PĂĄl Hospital, BĂŠkĂŠscsaba, Hungary
BMKK, PĂĄndy KĂĄlmĂĄn Hospital, Gyula, Hungary
BĂĄcs-Kiskun County University Teaching Hospital, KecskemĂŠt, Hungary
Dr. Bugyi IstvĂĄn Hospital of CsongrĂĄd County, Szentes, Hungary
Markusovszky Teaching Hospital, Szombathely, Szombathely, Hungary
First Department of Medicine, University of PĂŠcs, PĂŠcs, Hungary
MTAâSZTE Momentum Translational Gastroenterology Research Group, Szeged, Hungary
First Department of Surgery, Center for Therapeutic Endoscopy, Semmelweis University, Budapest, Hungary
Cited By :3
Export Date: 4 January 2021
CODEN: DLDIF
Correspondence Address: ErĹss, B.; Institute for Translational Medicine, Medical School, University of PĂŠcs, Szigeti str. 12, Hungary; email: eross.balint@pte.hu
Szent GyĂśrgy Teaching Hospital of FejĂŠr County, SzĂŠkesfehĂŠrvĂĄr, Hungary
Institute for Translational Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Institute of Bioanalysis and Institute for Translational Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Bajcsy-Zsilinszky Teaching Hospital of Semmelweis University, Budapest, Hungary
First Department of Medicine, University of Szeged, Szeged, Hungary
First Department of Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Heim PĂĄl National Institute for Pediatrics, Budapest, Hungary
BMKK, Dr. RĂŠthy PĂĄl Hospital, BĂŠkĂŠscsaba, Hungary
BMKK, PĂĄndy KĂĄlmĂĄn Hospital, Gyula, Hungary
BĂĄcs-Kiskun County University Teaching Hospital, KecskemĂŠt, Hungary
Dr. Bugyi IstvĂĄn Hospital of CsongrĂĄd County, Szentes, Hungary
Markusovszky Teaching Hospital, Szombathely, Szombathely, Hungary
First Department of Medicine, University of PĂŠcs, PĂŠcs, Hungary
MTAâSZTE Momentum Translational Gastroenterology Research Group, Szeged, Hungary
First Department of Surgery, Center for Therapeutic Endoscopy, Semmelweis University, Budapest, Hungary
Cited By :3
Export Date: 21 January 2021
CODEN: DLDIF
Correspondence Address: ErĹss, B.; Institute for Translational Medicine, Szigeti str. 12, Hungary; email: eross.balint@pte.hu
Szent GyĂśrgy Teaching Hospital of FejĂŠr County, SzĂŠkesfehĂŠrvĂĄr, Hungary
Institute for Translational Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Institute of Bioanalysis and Institute for Translational Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Bajcsy-Zsilinszky Teaching Hospital of Semmelweis University, Budapest, Hungary
First Department of Medicine, University of Szeged, Szeged, Hungary
First Department of Medicine, Medical School, University of PĂŠcs, PĂŠcs, Hungary
Heim PĂĄl National Institute for Pediatrics, Budapest, Hungary
BMKK, Dr. RĂŠthy PĂĄl Hospital, BĂŠkĂŠscsaba, Hungary
BMKK, PĂĄndy KĂĄlmĂĄn Hospital, Gyula, Hungary
BĂĄcs-Kiskun County University Teaching Hospital, KecskemĂŠt, Hungary
Dr. Bugyi IstvĂĄn Hospital of CsongrĂĄd County, Szentes, Hungary
Markusovszky Teaching Hospital, Szombathely, Szombathely, Hungary
First Department of Medicine, University of PĂŠcs, PĂŠcs, Hungary
MTAâSZTE Momentum Translational Gastroenterology Research Group, Szeged, Hungary
First Department of Surgery, Center for Therapeutic Endoscopy, Semmelweis University, Budapest, Hungary
Cited By :3
Export Date: 25 January 2021
CODEN: DLDIF
Correspondence Address: ErĹss, B.; Institute for Translational Medicine, Szigeti str. 12, Hungary; email: eross.balint@pte.hu
%A KollaborĂĄciĂłs szervezet: Hungarian Pancreatic Study Group
%A SzabĂł-HalĂĄsz Adrienn
%A PĂŠcsi DĂĄniel
%A BorbĂĄsnĂŠ Farkas KornĂŠlia
%A IzbĂŠki Ferenc
%A GajdĂĄn LĂĄszlĂł
%A Fejes Roland
%A Hamvas JĂłzsef
%A TakĂĄcs TamĂĄs
%A Szepes ZoltĂĄn
%A CzakĂł LĂĄszlĂł
%A Vincze Ăron
%A GĂłdi SzilĂĄrd
%A Szentesi Andrea IldikĂł
%A PĂĄrniczky Andrea
%A IllĂŠs DĂłra
%A Kui BalĂĄzs
%A VarjĂş PĂŠter
%A MĂĄrta Katalin
%A Varga MĂĄrta
%A NovĂĄk JĂĄnos
%A Szepes Attila
%A Bod BarnabĂĄs
%A IhĂĄsz MiklĂłs
%A Hegyi PĂŠter
%A Hritz IstvĂĄn
%A ErĹss BĂĄlint MihĂĄly
%R MTMT:30648945 10.1016/j.dld.2019.03.018
%L publicatio22006
%P 1281-1286
%V 51
%N 9