TY - JOUR SP - 161 N1 - FELTÖLT?: Surányi Andrea - gaspar-suranyi.andrea@med.u-szeged.hu TI - Use of placental vascularization indices and uterine artery peak systolic velocity in early detection of pregnancies complicated by gestational diabetes, chronic or gestational hypertension, and preeclampsia at risk EP - 169 JF - CROATIAN MEDICAL JOURNAL SN - 0353-9504 Y1 - 2017/// IS - 2 ID - publicatio11136 A1 - Altorjay Ábel T. A1 - Surányi Andrea A1 - Nyári Tibor András A1 - Németh Gábor AV - public N2 - Aim We aimed to investigate correlations between uterine artery peak systolic velocity (AUtPSV), and placental vascularization in groups of normal blood pressure (NBP) and hypertensive disorders of pregnancy (chronic hypertension (CHT), gestational hypertension (GHT) and preeclampsia (PE)) alone or in combination with gestational diabetes mellitus (GDM), and hypothesized that AUtPSV rises when GDM complicates pregnancy hypertension. Methods Placental 3-dimensional power Doppler indices, such as vascularization index (VI), flow index (FI), and vascularization-flow index (VFI), and uterine artery peak systolic velocity (AUtPSV) were measured in CHT (N = 43), CHT+GDM (N = 15), GHT (N = 57), GHT+GDM (N = 23) and PE (N = 17) pregnancies, and compared to NBP (N = 109). Correlations were analyzed between vascularization indices, AUtPSV, pregestational BMI and adverse pregnancy outcome rates. Results In our results VI was higher in CHT (P = 0.010), while FI was lower in CHT (P = 0.009), GHT and PE (P = 0.001) compared to NBP. In case of VFI, significant difference was found between CHT and GHT (P = 0.002), and NBP and PE (P = 0.001). FI was found prognostic for umbilical pH and neonatal birth weight. Pre-gestational BMI was significantly higher in GHT+GDM compared to GHT, and in CHT+GDM compared to the CHT group. As for AUtPSV, significant difference was found between NBP and CHT (P = 0.012), NBP and CHT+GDM (P = 0.045), NBP and GHT+GDM (P = 0.007), NBP and PE (P = 0.032), and GHT and GHT+GDM (P = 0.048) groups. Conclusion Our study revealed that vascularization indices and AUtPSV show significant differences due to gestational pathology, and can be useful in detection of pregnancies at risk. Use of placental vascularization indices and uterine artery peak systolic velocity in early detection of pregnancies complicated by gestational diabetes, chronic or gestational hypertension, and preeclampsia at risk. VL - 58 UR - http://publicatio.bibl.u-szeged.hu/11136/ ER -