relation: http://publicatio.bibl.u-szeged.hu/10616/ title: Knee Ankyloses Associated with Tuberculosis from the Medieval Hungary - Differential Diagnosis Based on Medical Imaging Techniques creator: Paja László creator: Coqueugniot H. creator: Dutour Olivier creator: Willmon R. creator: Farkas L. Gyula creator: Palkó András creator: Pálfi György description: Osseous ankylosis of large joints that occurs secondary to infection is rarely described in developed countries, thanks to diagnostic techniques that allow early detection and treatment of the underlying infection. Evidence of the natural history and progression of the disease is now primarily studied through the observation and analysis of osteoarcheological specimens, and medical reports or books dating from the pre-antibiotic era. This report illustrates several cases where modern medical imaging techniques and ancient medical literature were successfully interpreted to diagnose rare, advanced-stage tuberculous alterations in osteoarcheological specimens. Two skeletons from the Bátmonostor cemetery (Hungary) demonstrate complete unilateral ankylosis of the knee. Macroscopic and radiographic examinations were undertaken to assess the extent of skeletal changes and determine their cause. Data obtained from computed tomography (CT) were constructed in 2D and 3D. The 2D CT images revealed cavities involving both the metaphyses and the epiphyses. The 3D reconstructions allowed us to reconstruct the more precise volumetric morphology of the circumscribed lytic lesions, as well as clear 'image-mirror' lacunar volumes. On the basis of the macroscopic and radiological analyses, extra-spinal tuberculous infection seems to have been the most probable etiology of these two cases. © 2012 John Wiley & Sons, Ltd. publisher: John Wiley & Sons; Scrivener date: 2015 type: Folyóiratcikk type: PeerReviewed format: text identifier: http://publicatio.bibl.u-szeged.hu/10616/1/10.pdf identifier: Paja László; Coqueugniot H.; Dutour Olivier; Willmon R.; Farkas L. Gyula; Palkó András; Pálfi György: Knee Ankyloses Associated with Tuberculosis from the Medieval Hungary - Differential Diagnosis Based on Medical Imaging Techniques. INTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, 25 (3). pp. 352-360. ISSN 1047-482X (2015) identifier: doi:10.1002/oa.2284 relation: 2721450 language: eng relation: info:eu-repo/semantics/altIdentifier/doi/10.1002/oa.2284 rights: info:eu-repo/semantics/restrictedAccess