TY - JOUR Y1 - 2015/// UR - http://publicatio.bibl.u-szeged.hu/10040/ TI - Ageing of the vitreous: From acute onset floaters and flashes to retinal detachment EP - 77 SP - 71 N2 - Floaters and flashes are most commonly symptoms of age-related degenerative changes in the vitreous body and posterior vitreous detachment. The etiology and pathogenesis of floaters' formation is still not well understood. Patients with acute-onset floaters, flashes and defects in their visual field, represent a medical emergency with the need for same day referral to an ophthalmologist. Indirect ophthalmoscopy with scleral indentation is needed in order to find possible retinal break(s), on-time treatment and prevention of retinal detachment. The molecular and genetic pathogenesis, as well as the epidemiology of the ageing changes of the vitreous is summarized here, with view on the several treatment modalities in relation to their success rate and side-effects. SN - 1568-1637 N1 - FELTÖLT?: Albert Réka - albertreka86@gmail.com VL - 21 JF - AGEING RESEARCH REVIEWS A1 - Lumi Xhevat A1 - Hawlina Marko A1 - Glavac Damjan A1 - Facskó Andrea A1 - Moe Morten C. A1 - Kaarniranta Kai A1 - Petrovski Goran AV - restricted ID - publicatio10040 ER -